There are a lot of ways to backup your MOSS environment. When it comes to Farms you will even need more then one backup and restore system. Some backup and restore mechanisms like the inbuild one in MOSS itself depends on how you actually divided your content structure over site collections. I composed the following list of backup and restore tools, based on some great posts like the one of Joel Oleson.
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Native SQL Server Backup & Restore
Native backup & Restore products for all your databases. Like SQL Backup and SQL Safe
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Data Protection Manager 2007
A complete Microsoft solution with System Center Data Protection Manager (DPM) 2007 for ways to protect and recover SharePoint collaboration infrastructures.
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Farm and Granular Backup and recovery tool DocAve
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Neverfail tool which provides End-to-End High Availability and Disaster Recovery for SharePoint Environments
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Webcast:
Webcast: SharePoint Server 2007 (Part 3 of 6): Disaster Recovery (Level 200)
More resources:
http://blogs.msdn.com/joelo/archive/2007/03/09/sharepoint-backup-restore-high-availability-and-disaster-recovery.aspx
http://blogs.msdn.com/ronalg/archive/2007/08/16/moss2007-wssv3-restore-feature-issue.aspx
http://blogs.msdn.com/sharepoint/archive/2007/10/25/sharepoint-backup-and-restore-resources.aspx
There is a lot more but the most interesting stuff is mentioned.